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Propranolol inhibits the proliferation, migration and tube formation of hemangioma cells through HIF-1α dependent mechanisms

The aim of this study was to investigate the mechanism of propranolol on the regression of hemangiomas. Propranolol-treated hemangioma tissues were collected and the expression of hypoxia inducible factor-1α (HIF-1α) was examined. We also established HIF-1α overexpression and knockdown hemangioma ce...

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Detalles Bibliográficos
Autores principales: Chen, Y.Z., Bai, N., Bi, J.H., Liu, X.W., Xu, G.Q., Zhang, L.F., Li, X.Q., Huo, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625545/
https://www.ncbi.nlm.nih.gov/pubmed/28977119
http://dx.doi.org/10.1590/1414-431X20176138