Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis

Macrophage M1/M2 polarization mediates tissue damage and inflammatory responses. Cannabinoid receptor (CB) 1 participated in liver fibrogenesis by affecting bone marrow (BM)-derived monocytes/macrophages (BMMs) activation. However, the knowledge of whether CB1 is involved in the polarization of BMMs...

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Detalles Bibliográficos
Autores principales: Tian, Lei, Li, Weiyang, Yang, Le, Chang, Na, Fan, Xiaoting, Ji, Xiaofang, Xie, Jieshi, Yang, Lin, Li, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625548/
https://www.ncbi.nlm.nih.gov/pubmed/29033935
http://dx.doi.org/10.3389/fimmu.2017.01214

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