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High-throughput RNAi screen for essential genes and drug synergistic combinations in colorectal cancer

Metastatic colorectal cancer is a leading cause of cancer death. However, current therapy options are limited to chemotherapy, with the addition of anti-EGFR antibodies for patients with RAS wild-type tumours. Novel drug targets, or drug combinations that induce a synergistic response, would be of g...

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Detalles Bibliográficos
Autores principales:	Williams, Steven P., Barthorpe, Andrew S., Lightfoot, Howard, Garnett, Mathew J., McDermott, Ultan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Data Descriptor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625556/ https://www.ncbi.nlm.nih.gov/pubmed/28972570 http://dx.doi.org/10.1038/sdata.2017.139

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