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Cryptococcal cerebellitis in no-VIH patient

INTRODUCTION: Cryptococcosis is an opportunistic fungal infection whose etiology is Cryptococcus neofromans / C. gattii, complex which affects immunocompromised patients mainly. Meningeal infection is one of the most common presentations, but cerebellar affection is rare. CASE DESCRIPTION: Male pati...

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Autores principales: Lasso, Fabricio Andres, Zamora Bastidas, Tomas Omar, Potosí García, Jorge Andrés, Díaz Idrobo, Bairon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Universidad del Valle 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625563/
https://www.ncbi.nlm.nih.gov/pubmed/29021643
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author Lasso, Fabricio Andres
Zamora Bastidas, Tomas Omar
Potosí García, Jorge Andrés
Díaz Idrobo, Bairon
author_facet Lasso, Fabricio Andres
Zamora Bastidas, Tomas Omar
Potosí García, Jorge Andrés
Díaz Idrobo, Bairon
author_sort Lasso, Fabricio Andres
collection PubMed
description INTRODUCTION: Cryptococcosis is an opportunistic fungal infection whose etiology is Cryptococcus neofromans / C. gattii, complex which affects immunocompromised patients mainly. Meningeal infection is one of the most common presentations, but cerebellar affection is rare. CASE DESCRIPTION: Male patient with 65 old years, from an area of subtropical climate with chronic exposure to poultry, without pathological antecedents, who presented clinical picture consistent with headache, fever, seizures and altered mental status. CLINICAL FINDINGS AND DIAGNOSTIC METHODS: Initially without menigeal signs or intracranial hypertension and normal neurological examination. Later, the patient developed ataxia, dysdiadochokinesia and limb loss. By lumbar punction and image of nuclear magnetic resonance (NMR) cerebellitis cryptococcal was diagnosticated. TREATMENT: Antifungal therapy with amphotericin B and fluconazole was performed, however the patient died. CLINICAL RELEVANCE: The cryptococcosis has different presentations, it´s a disease whose incidence has been increasing since the advent of the HIV / AIDS pandemy, however the commitment of the encephalic parenchyma and in particular the cerebellum is considered rare. In this way we are facing the first case of cryptococcal cerebellitis in our midst.
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spelling pubmed-56255632017-10-11 Cryptococcal cerebellitis in no-VIH patient Lasso, Fabricio Andres Zamora Bastidas, Tomas Omar Potosí García, Jorge Andrés Díaz Idrobo, Bairon Colomb Med (Cali) Case Report INTRODUCTION: Cryptococcosis is an opportunistic fungal infection whose etiology is Cryptococcus neofromans / C. gattii, complex which affects immunocompromised patients mainly. Meningeal infection is one of the most common presentations, but cerebellar affection is rare. CASE DESCRIPTION: Male patient with 65 old years, from an area of subtropical climate with chronic exposure to poultry, without pathological antecedents, who presented clinical picture consistent with headache, fever, seizures and altered mental status. CLINICAL FINDINGS AND DIAGNOSTIC METHODS: Initially without menigeal signs or intracranial hypertension and normal neurological examination. Later, the patient developed ataxia, dysdiadochokinesia and limb loss. By lumbar punction and image of nuclear magnetic resonance (NMR) cerebellitis cryptococcal was diagnosticated. TREATMENT: Antifungal therapy with amphotericin B and fluconazole was performed, however the patient died. CLINICAL RELEVANCE: The cryptococcosis has different presentations, it´s a disease whose incidence has been increasing since the advent of the HIV / AIDS pandemy, however the commitment of the encephalic parenchyma and in particular the cerebellum is considered rare. In this way we are facing the first case of cryptococcal cerebellitis in our midst. Universidad del Valle 2017-06-30 /pmc/articles/PMC5625563/ /pubmed/29021643 Text en Copyright © 2017 Universidad del Valle This article is distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Case Report
Lasso, Fabricio Andres
Zamora Bastidas, Tomas Omar
Potosí García, Jorge Andrés
Díaz Idrobo, Bairon
Cryptococcal cerebellitis in no-VIH patient
title Cryptococcal cerebellitis in no-VIH patient
title_full Cryptococcal cerebellitis in no-VIH patient
title_fullStr Cryptococcal cerebellitis in no-VIH patient
title_full_unstemmed Cryptococcal cerebellitis in no-VIH patient
title_short Cryptococcal cerebellitis in no-VIH patient
title_sort cryptococcal cerebellitis in no-vih patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625563/
https://www.ncbi.nlm.nih.gov/pubmed/29021643
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