Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228)

BACKGROUND: The hepatic artery infusion (HAI) of irinotecan, oxaliplatin and 5-fluorouracil with intravenous cetuximab achieved outstanding efficacy in previously treated patients with initially unresectable liver metastases from colorectal cancer. This planned study aimed at the identification of p...

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Detalles Bibliográficos
Autores principales: Lévi, Francis, Karaboué, Abdoulaye, Saffroy, Raphaël, Desterke, Christophe, Boige, Valerie, Smith, Denis, Hebbar, Mohamed, Innominato, Pasquale, Taieb, Julien, Carvalho, Carlos, Guimbaud, Rosine, Focan, Christian, Bouchahda, Mohamed, Adam, René, Ducreux, Michel, Milano, Gérard, Lemoine, Antoinette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625679/
https://www.ncbi.nlm.nih.gov/pubmed/28817838
http://dx.doi.org/10.1038/bjc.2017.278

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