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Suppression of SIRT2 and altered acetylation status of human pluripotent stem cells: possible link to metabolic switch during reprogramming

Primed human pluripotent stem cells (hPSCs) are highly dependent on glycolysis rather than oxidative phosphorylation, which is similar to the metabolic switch that occurs in cancer cells. However, the molecular mechanisms that underlie this metabolic reprogramming in hPSCs and its relevance to pluri...

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Detalles Bibliográficos
Autores principales:	Kwon, Ok-Seon, Han, Min-Joon, Cha, Hyuk-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2017
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625689/ https://www.ncbi.nlm.nih.gov/pubmed/28683850 http://dx.doi.org/10.5483/BMBRep.2017.50.9.119

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