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Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4(+) T cells

The transcription repressor Bach2 has been proposed as a regulator of T cell quiescence, but the underlying mechanism is not fully understood. Given the importance of interleukin-2 in T cell activation, we investigated whether Bach2 is a component of the network of factors that regulates interleukin...

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Detalles Bibliográficos
Autores principales: Jang, Eunkyeong, Lee, Hye Rim, Lee, Geon Hee, Oh, Ah-Reum, Cha, Ji-Young, Igarashi, Kazuhiko, Youn, Jeehee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625695/
https://www.ncbi.nlm.nih.gov/pubmed/28855027
http://dx.doi.org/10.5483/BMBRep.2017.50.9.124