Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance

BACKGROUND: Adenosine to inosine (A-to-I) RNA editing is a post-transcriptional modification catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are ubiquitously expressed among metazoans. Technical requirements have limited systematic mapping of editing sites to a small numb...

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Detalles Bibliográficos
Autores principales: Porath, Hagit T., Knisbacher, Binyamin A., Eisenberg, Eli, Levanon, Erez Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625713/
https://www.ncbi.nlm.nih.gov/pubmed/28969707
http://dx.doi.org/10.1186/s13059-017-1315-y

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