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Role of PCNA and RFC in promoting Mus81-complex activity

BACKGROUND: Proper DNA replication is essential for faithful transmission of the genome. However, replication stress has serious impact on the integrity of the cell, leading to stalling or collapse of replication forks, and has been determined as a driving force of carcinogenesis. Mus81-Mms4 complex...

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Detalles Bibliográficos
Autores principales:	Sisakova, Alexandra, Altmannova, Veronika, Sebesta, Marek, Krejci, Lumir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625722/ https://www.ncbi.nlm.nih.gov/pubmed/28969641 http://dx.doi.org/10.1186/s12915-017-0429-8

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