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Heterologous expression of Avermectins biosynthetic gene cluster by construction of a Bacterial Artificial Chromosome library of the producers

Avermectins, a group of polyketide natural products, are widely used as anthelmintics in agriculture. Metabolic engineering and combinatorial biosynthesis were extensively employed to improve Avermectins production and create novel Avermectin derivatives, including Ivermectin and Doramectin. It is l...

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Detalles Bibliográficos
Autores principales:	Deng, Qian, Zhou, Li, Luo, Meizhong, Deng, Zixin, Zhao, Changming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	KeAi Publishing 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625734/ https://www.ncbi.nlm.nih.gov/pubmed/29062962 http://dx.doi.org/10.1016/j.synbio.2017.03.001

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