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ARF1 recruits RAC1 to leading edge in neutrophil chemotaxis

BACKGROUND: The small GTPase ARF1 mediates membrane trafficking mostly from the Golgi, and is essential for the G protein-coupled receptor (GPCR)-mediated chemotaxis of neutrophils. In this process, ARF1 is activated by the guanine nucleotide exchanger GBF1, and is inactivated by the GTPase-activati...

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Detalles Bibliográficos
Autores principales:	Mazaki, Yuichi, Onodera, Yasuhito, Higashi, Tsunehito, Horinouchi, Takahiro, Oikawa, Tsukasa, Sabe, Hisataka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625764/ https://www.ncbi.nlm.nih.gov/pubmed/28969640 http://dx.doi.org/10.1186/s12964-017-0193-y

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