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Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis

Osteoclasts are large multinucleated cells responsible for bone resorption. Excessive inflammatory activation of osteoclasts leads to bony erosions, which are the hallmark of several diseases such as rheumatoid arthritis (RA). Salt-inducible kinases (SIK) constitute a subfamily of kinases comprising...

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Detalles Bibliográficos
Autores principales:	Lombardi, Maria Stella, Gilliéron, Corine, Berkelaar, Majoska, Gabay, Cem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626034/ https://www.ncbi.nlm.nih.gov/pubmed/28973003 http://dx.doi.org/10.1371/journal.pone.0185426

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