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Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases

The association of varicoceles with infertility is well established, but the exact effect of varicoceles on semen quality among patients with infertility is still poorly known. The study aimed to examine the prevalence of varicoceles among Chinese men with infertility and to examine the factors asso...

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Autores principales: Zhang, Yunshan, Ma, Tianzhong, Su, Zexuan, Ye, Mushi, Tian, Huanshu, Li, Jianchang, Liu, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626160/
https://www.ncbi.nlm.nih.gov/pubmed/28767606
http://dx.doi.org/10.1097/MD.0000000000007707
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author Zhang, Yunshan
Ma, Tianzhong
Su, Zexuan
Ye, Mushi
Tian, Huanshu
Li, Jianchang
Liu, Jianjun
author_facet Zhang, Yunshan
Ma, Tianzhong
Su, Zexuan
Ye, Mushi
Tian, Huanshu
Li, Jianchang
Liu, Jianjun
author_sort Zhang, Yunshan
collection PubMed
description The association of varicoceles with infertility is well established, but the exact effect of varicoceles on semen quality among patients with infertility is still poorly known. The study aimed to examine the prevalence of varicoceles among Chinese men with infertility and to examine the factors associated with semen quality. This was a cross-sectional study of 5447 male patients treated for infertility at the Affiliated Hospital of Guangdong Medical University from October 2012 to December 2015. The patients were divided on the basis of the presence of varicoceles. Examinations of the amount of semen and sperm morphology were performed according to seminal parameter detection methods recommended by the World Health Organization. Patients with varicoceles (n = 1429/5447, 26.2%) were slightly younger (P = .046), and had smaller testis (P = .019), higher frequency of abnormal epididymis (P < .001), slightly shorter infertility duration (P = .046), and lower frequency of smokers (P = .012). There was no difference in the distribution of occupations (P = .777). Using multiple linear regression analysis, varicoceles were shown to be independently associated with semen volume [B = −0.153, 95% confidence interval (95% CI): −0.245 to −0.062, P = .001], sperm concentration (B = 9.633, 95% CI: 7.152–12.114, P < .001), proportion of sperms with normal morphology (B = 0.951, 95% CI: 0.623–1.278, P < .001), motility (B = 3.835, 95% CI: 2.675, 4.995, P < .001), total sperm count (B = 22.481, 95% CI: 13.333–31.629, P < .001), and forward movement sperm count (B = 15.553, 95% CI: 9.777–21.329, P < .001). Varicoceles were present in 26% of Chinese male patients with infertility. Varicoceles were independently associated with sperm volume, sperm concentration, proportion of sperms with normal morphology, motility, total sperm count, and forward movement sperm count.
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spelling pubmed-56261602017-10-11 Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases Zhang, Yunshan Ma, Tianzhong Su, Zexuan Ye, Mushi Tian, Huanshu Li, Jianchang Liu, Jianjun Medicine (Baltimore) 7300 The association of varicoceles with infertility is well established, but the exact effect of varicoceles on semen quality among patients with infertility is still poorly known. The study aimed to examine the prevalence of varicoceles among Chinese men with infertility and to examine the factors associated with semen quality. This was a cross-sectional study of 5447 male patients treated for infertility at the Affiliated Hospital of Guangdong Medical University from October 2012 to December 2015. The patients were divided on the basis of the presence of varicoceles. Examinations of the amount of semen and sperm morphology were performed according to seminal parameter detection methods recommended by the World Health Organization. Patients with varicoceles (n = 1429/5447, 26.2%) were slightly younger (P = .046), and had smaller testis (P = .019), higher frequency of abnormal epididymis (P < .001), slightly shorter infertility duration (P = .046), and lower frequency of smokers (P = .012). There was no difference in the distribution of occupations (P = .777). Using multiple linear regression analysis, varicoceles were shown to be independently associated with semen volume [B = −0.153, 95% confidence interval (95% CI): −0.245 to −0.062, P = .001], sperm concentration (B = 9.633, 95% CI: 7.152–12.114, P < .001), proportion of sperms with normal morphology (B = 0.951, 95% CI: 0.623–1.278, P < .001), motility (B = 3.835, 95% CI: 2.675, 4.995, P < .001), total sperm count (B = 22.481, 95% CI: 13.333–31.629, P < .001), and forward movement sperm count (B = 15.553, 95% CI: 9.777–21.329, P < .001). Varicoceles were present in 26% of Chinese male patients with infertility. Varicoceles were independently associated with sperm volume, sperm concentration, proportion of sperms with normal morphology, motility, total sperm count, and forward movement sperm count. Wolters Kluwer Health 2017-08-04 /pmc/articles/PMC5626160/ /pubmed/28767606 http://dx.doi.org/10.1097/MD.0000000000007707 Text en Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0
spellingShingle 7300
Zhang, Yunshan
Ma, Tianzhong
Su, Zexuan
Ye, Mushi
Tian, Huanshu
Li, Jianchang
Liu, Jianjun
Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases
title Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases
title_full Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases
title_fullStr Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases
title_full_unstemmed Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases
title_short Varicoceles affect semen quality of infertile men in Southern China: A cross-sectional study of 5447 cases
title_sort varicoceles affect semen quality of infertile men in southern china: a cross-sectional study of 5447 cases
topic 7300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626160/
https://www.ncbi.nlm.nih.gov/pubmed/28767606
http://dx.doi.org/10.1097/MD.0000000000007707
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