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A novel haplotype of low-frequency variants in the aldosterone synthase gene among northern Han Chinese with essential hypertension

Low-frequency variants showed that there is more power to detect risk variants than to detect protective variants in complex diseases. Aldosterone plays an important role in the renin–angiotensin–aldosterone system, and aldosterone synthase catalyzes the speed-controlled steps of aldosterone biosynt...

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Detalles Bibliográficos
Autores principales:	Zhang, Hao, Li, Xueyan, Zhou, Li, Zhang, Keyong, Zhang, Qi, Li, Jingping, Wang, Ningning, Jin, Ming, Wu, Nan, Cong, Mingyu, Qiu, Changchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2017
Materias:	3400
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626300/ https://www.ncbi.nlm.nih.gov/pubmed/28953657 http://dx.doi.org/10.1097/MD.0000000000008150

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