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Predicting treatment outcomes of major depressive disorder by early improvement in painful physical symptoms: a pooled analysis of double-blind, placebo-controlled trials of duloxetine
OBJECTIVE: We determined if early improvement in painful physical symptoms (PPS) can be a predictor of remission in the treatment of major depressive disorder (MDD). METHODS: We included randomized, double-blind, parallel-group clinical trials of duloxetine (40–60 mg/day) versus placebo for the acut...
Autores principales: | Tokuoka, Hirofumi, Nishihara, Makoto, Fujikoshi, Shinji, Yoshikawa, Aki, Kuga, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626379/ https://www.ncbi.nlm.nih.gov/pubmed/29026309 http://dx.doi.org/10.2147/NDT.S143093 |
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