Transient apoptosis inhibition in donor stem cells improves hematopoietic stem cell transplantation

During hematopoietic stem cell transplantation, a substantial number of donor cells are lost because of apoptotic cell death. Transplantation-associated apoptosis is mediated mainly by the proapoptotic BCL-2 family proteins BIM and BMF, and their proapoptotic function is conserved between mouse and...

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Detalles Bibliográficos
Autores principales: Kollek, Matthias, Voigt, Gesina, Molnar, Christian, Murad, Fabronia, Bertele, Daniela, Krombholz, Christopher Felix, Bohler, Sheila, Labi, Verena, Schiller, Stefan, Kunze, Mirjam, Geley, Stephan, Niemeyer, Charlotte M., Garcia-Saez, Ana, Erlacher, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626392/
https://www.ncbi.nlm.nih.gov/pubmed/28882984
http://dx.doi.org/10.1084/jem.20161721

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