LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection

Although genetic polymorphisms in the LRRK2 gene are associated with a variety of diseases, the physiological function of LRRK2 remains poorly understood. In this study, we report a crucial role for LRRK2 in the activation of the NLRC4 inflammasome during host defense against Salmonella enteric sero...

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Detalles Bibliográficos
Autores principales: Liu, Weiwei, Liu, Xia’nan, Li, Yu, Zhao, Junjie, Liu, Zhenshan, Hu, Zhuqin, Wang, Ying, Yao, Yufeng, Miller, Aaron W., Su, Bing, Cookson, Mark R., Li, Xiaoxia, Kang, Zizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626397/
https://www.ncbi.nlm.nih.gov/pubmed/28821568
http://dx.doi.org/10.1084/jem.20170014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626397/
https://www.ncbi.nlm.nih.gov/pubmed/28821568
http://dx.doi.org/10.1084/jem.20170014

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