EGF hijacks miR-198/FSTL1 wound-healing switch and steers a two-pronged pathway toward metastasis

Epithelial carcinomas are well known to activate a prolonged wound-healing program that promotes malignant transformation. Wound closure requires the activation of keratinocyte migration via a dual-state molecular switch. This switch involves production of either the anti-migratory microRNA miR-198...

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Detalles Bibliográficos
Autores principales: Sundaram, Gopinath M., Ismail, Hisyam M., Bashir, Mohsin, Muhuri, Manish, Vaz, Candida, Nama, Srikanth, Ow, Ghim Siong, Vladimirovna, Ivshina Anna, Ramalingam, Rajkumar, Burke, Brian, Tanavde, Vivek, Kuznetsov, Vladimir, Lane, E. Birgitte, Sampath, Prabha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626400/
https://www.ncbi.nlm.nih.gov/pubmed/28827448
http://dx.doi.org/10.1084/jem.20170354

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