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Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling

The mouse Langerhans cell (LC) network is established through the differentiation of embryonic LC precursors. BMP7 and TGFβ1 initiate cellular signaling that is essential for inducing LC differentiation and preserving LCs in a quiescent state, respectively. Here we show that loss of Cbfβ2, one of tw...

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Detalles Bibliográficos
Autores principales:	Tenno, Mari, Shiroguchi, Katsuyuki, Muroi, Sawako, Kawakami, Eiryo, Koseki, Keita, Kryukov, Kirill, Imanishi, Tadashi, Ginhoux, Florent, Taniuchi, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626404/ https://www.ncbi.nlm.nih.gov/pubmed/28814567 http://dx.doi.org/10.1084/jem.20170729

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