LARP4 mRNA codon-tRNA match contributes to LARP4 activity for ribosomal protein mRNA poly(A) tail length protection

Messenger RNA function is controlled by the 3' poly(A) tail (PAT) and poly(A)-binding protein (PABP). La-related protein-4 (LARP4) binds poly(A) and PABP. LARP4 mRNA contains a translation-dependent, coding region determinant (CRD) of instability that limits its expression. Although the CRD com...

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Detalles Bibliográficos
Autores principales: Mattijssen, Sandy, Arimbasseri, Aneeshkumar G, Iben, James R, Gaidamakov, Sergei, Lee, Joowon, Hafner, Markus, Maraia, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626478/
https://www.ncbi.nlm.nih.gov/pubmed/28895529
http://dx.doi.org/10.7554/eLife.28889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626478/
https://www.ncbi.nlm.nih.gov/pubmed/28895529
http://dx.doi.org/10.7554/eLife.28889

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