A synthetic biology approach to probing nucleosome symmetry

The repeating subunit of chromatin, the nucleosome, includes two copies of each of the four core histones, and several recent studies have reported that asymmetrically-modified nucleosomes occur at regulatory elements in vivo. To probe the mechanisms by which histone modifications are read out, we d...

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Detalles Bibliográficos
Autores principales: Ichikawa, Yuichi, Connelly, Caitlin F, Appleboim, Alon, Miller, Thomas CR, Jacobi, Hadas, Abshiru, Nebiyu A, Chou, Hsin-Jung, Chen, Yuanyuan, Sharma, Upasna, Zheng, Yupeng, Thomas, Paul M, Chen, Hsuiyi V, Bajaj, Vineeta, Müller, Christoph W, Kelleher, Neil L, Friedman, Nir, Bolon, Daniel NA, Rando, Oliver J, Kaufman, Paul D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626479/
https://www.ncbi.nlm.nih.gov/pubmed/28895528
http://dx.doi.org/10.7554/eLife.28836

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