Diminished neutrophil extracellular trap (NET) formation is a novel innate immune deficiency induced by acute ethanol exposure in polymicrobial sepsis, which can be rescued by CXCL1

Polymicrobial sepsis is the result of an exaggerated host immune response to bacterial pathogens. Animal models and human studies demonstrate that alcohol intoxication is a key risk factor for sepsis-induced mortality. Multiple chemokines, such as CXCL1, CXCL2 and CXCL5 are critical for neutrophil r...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Liliang, Batra, Sanjay, Jeyaseelan, Samithamby
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626520/
https://www.ncbi.nlm.nih.gov/pubmed/28922428
http://dx.doi.org/10.1371/journal.ppat.1006637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626520/
https://www.ncbi.nlm.nih.gov/pubmed/28922428
http://dx.doi.org/10.1371/journal.ppat.1006637

Ejemplares similares