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EB1 and EB3 regulate microtubule minus end organization and Golgi morphology
End-binding proteins (EBs) are the core components of microtubule plus end tracking protein complexes, but it is currently unknown whether they are essential for mammalian microtubule organization. Here, by using CRISPR/Cas9-mediated knockout technology, we generated stable cell lines lacking EB2 an...
Autores principales: | Yang, Chao, Wu, Jingchao, de Heus, Cecilia, Grigoriev, Ilya, Liv, Nalan, Yao, Yao, Smal, Ihor, Meijering, Erik, Klumperman, Judith, Qi, Robert Z., Akhmanova, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626540/ https://www.ncbi.nlm.nih.gov/pubmed/28814570 http://dx.doi.org/10.1083/jcb.201701024 |
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