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WDR91 is a Rab7 effector required for neuronal development
Early-to-late endosome conversion, which is essential for delivery of endosomal cargoes to lysosomes, requires switching of early endosome–specific Rab5 and PtdIns3P to late endosome–specific Rab7 and PtdIns(3,5)P(2). In this study, we identify the WD40-repeat protein WDR91 as a Rab7 effector that c...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626554/ https://www.ncbi.nlm.nih.gov/pubmed/28860274 http://dx.doi.org/10.1083/jcb.201705151 |