WDR91 is a Rab7 effector required for neuronal development

Early-to-late endosome conversion, which is essential for delivery of endosomal cargoes to lysosomes, requires switching of early endosome–specific Rab5 and PtdIns3P to late endosome–specific Rab7 and PtdIns(3,5)P(2). In this study, we identify the WD40-repeat protein WDR91 as a Rab7 effector that c...

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Detalles Bibliográficos
Autores principales: Liu, Kai, Xing, Ruxiao, Jian, Youli, Gao, Zhiyang, Ma, Xinli, Sun, Xiaojuan, Li, Yang, Xu, Meng, Wang, Xin, Jing, Yudong, Guo, Weixiang, Yang, Chonglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626554/
https://www.ncbi.nlm.nih.gov/pubmed/28860274
http://dx.doi.org/10.1083/jcb.201705151

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