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Catch and release: 14-3-3 controls Ncd in meiotic spindles

During Drosophila melanogaster oogenesis, spindle assembly occurs without centrosomes and relies on signals from chromosomes. Beaven et al. (2017. J. Cell. Biol. https://doi.org/10.1083/jcb.201704120) show that 14-3-3 proteins bind and inhibit a key microtubule motor, Ncd, during oogenesis, but Auro...

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Detalles Bibliográficos
Autor principal: Dasso, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626556/
https://www.ncbi.nlm.nih.gov/pubmed/28923976
http://dx.doi.org/10.1083/jcb.201708036
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author Dasso, Mary
author_facet Dasso, Mary
author_sort Dasso, Mary
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description During Drosophila melanogaster oogenesis, spindle assembly occurs without centrosomes and relies on signals from chromosomes. Beaven et al. (2017. J. Cell. Biol. https://doi.org/10.1083/jcb.201704120) show that 14-3-3 proteins bind and inhibit a key microtubule motor, Ncd, during oogenesis, but Aurora B releases Ncd inhibition near chromosomes, allowing Ncd to work in the right time and place.
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spelling pubmed-56265562018-04-02 Catch and release: 14-3-3 controls Ncd in meiotic spindles Dasso, Mary J Cell Biol Commentary During Drosophila melanogaster oogenesis, spindle assembly occurs without centrosomes and relies on signals from chromosomes. Beaven et al. (2017. J. Cell. Biol. https://doi.org/10.1083/jcb.201704120) show that 14-3-3 proteins bind and inhibit a key microtubule motor, Ncd, during oogenesis, but Aurora B releases Ncd inhibition near chromosomes, allowing Ncd to work in the right time and place. The Rockefeller University Press 2017-10-02 /pmc/articles/PMC5626556/ /pubmed/28923976 http://dx.doi.org/10.1083/jcb.201708036 Text en This is a work of the U.S. Government and is not subject to copyright protection in the United States. Foreign copyrights may apply. http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentary
Dasso, Mary
Catch and release: 14-3-3 controls Ncd in meiotic spindles
title Catch and release: 14-3-3 controls Ncd in meiotic spindles
title_full Catch and release: 14-3-3 controls Ncd in meiotic spindles
title_fullStr Catch and release: 14-3-3 controls Ncd in meiotic spindles
title_full_unstemmed Catch and release: 14-3-3 controls Ncd in meiotic spindles
title_short Catch and release: 14-3-3 controls Ncd in meiotic spindles
title_sort catch and release: 14-3-3 controls ncd in meiotic spindles
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626556/
https://www.ncbi.nlm.nih.gov/pubmed/28923976
http://dx.doi.org/10.1083/jcb.201708036
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