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Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission
The role of metabolites produced from stem cell metabolism has been emerged as signaling molecules to regulate stem cell behaviors such as migration. The mitochondrial morphology is closely associated with the metabolic balance and stem cell function. However, the physiological role of succinate on...
Autores principales: | Ko, So Hee, Choi, Gee Euhn, Oh, Ji Young, Lee, Hyun Jik, Kim, Jun Sung, Chae, Chang Woo, Choi, Diana, Han, Ho Jae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626702/ https://www.ncbi.nlm.nih.gov/pubmed/28974722 http://dx.doi.org/10.1038/s41598-017-12692-x |
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