Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer’s disease and progressive supranuclear palsy brains

Alternative promoter usage is an important mechanism for transcriptome diversity and the regulation of gene expression. Indeed, this alternative usage may influence tissue/subcellular specificity, protein translation and function of the proteins. The existence of an alternative promoter for MAPT gen...

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Detalles Bibliográficos
Autores principales: Huin, Vincent, Buée, Luc, Behal, Hélène, Labreuche, Julien, Sablonnière, Bernard, Dhaenens, Claire-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626709/
https://www.ncbi.nlm.nih.gov/pubmed/28974731
http://dx.doi.org/10.1038/s41598-017-12955-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626709/
https://www.ncbi.nlm.nih.gov/pubmed/28974731
http://dx.doi.org/10.1038/s41598-017-12955-7

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