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Alternative promoter usage generates novel shorter MAPT mRNA transcripts in Alzheimer’s disease and progressive supranuclear palsy brains
Alternative promoter usage is an important mechanism for transcriptome diversity and the regulation of gene expression. Indeed, this alternative usage may influence tissue/subcellular specificity, protein translation and function of the proteins. The existence of an alternative promoter for MAPT gen...
Autores principales: | Huin, Vincent, Buée, Luc, Behal, Hélène, Labreuche, Julien, Sablonnière, Bernard, Dhaenens, Claire-Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626709/ https://www.ncbi.nlm.nih.gov/pubmed/28974731 http://dx.doi.org/10.1038/s41598-017-12955-7 |
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