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Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation

Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F) protein, which carries out the process of virus-...

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Detalles Bibliográficos
Autores principales: Wong, Joyce J. W., Young, Tracy A., Zhang, Jiayan, Liu, Shiheng, Leser, George P., Komives, Elizabeth A., Lamb, Robert A., Zhou, Z. Hong, Salafsky, Joshua, Jardetzky, Theodore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626764/
https://www.ncbi.nlm.nih.gov/pubmed/28974687
http://dx.doi.org/10.1038/s41467-017-00863-3