Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-γ and multiple toll-like receptor agonists

Dendritic cell (DC) vaccines have been demonstrated to elicit immunological responses in numerous cancer immunotherapy trials. However, long-lasting clinical effects are infrequent. We therefore sought to establish a protocol to generate DC with greater immunostimulatory capacity. Immature DC were g...

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Detalles Bibliográficos
Autores principales: Lövgren, Tanja, Sarhan, Dhifaf, Truxová, Iva, Choudhary, Bhavesh, Maas, Roeltje, Melief, Jeroen, Nyström, Maria, Edbäck, Ulrika, Vermeij, Renee, Scurti, Gina, Nishimura, Michael, Masucci, Giuseppe, Karlsson-Parra, Alex, Lundqvist, Andreas, Adamson, Lars, Kiessling, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626805/
https://www.ncbi.nlm.nih.gov/pubmed/28601925
http://dx.doi.org/10.1007/s00262-017-2029-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626805/
https://www.ncbi.nlm.nih.gov/pubmed/28601925
http://dx.doi.org/10.1007/s00262-017-2029-4

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