Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties

Glutathione (GSH), a major cellular antioxidant, is considered an inhibitor of the inflammatory response involving reactive oxygen species (ROS). However, evidence is largely based on experiments with exogenously added antioxidants/reducing agents or pro-oxidants. We show that depleting macrophages...

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Detalles Bibliográficos
Autores principales: Diotallevi, Marina, Checconi, Paola, Palamara, Anna Teresa, Celestino, Ignacio, Coppo, Lucia, Holmgren, Arne, Abbas, Kahina, Peyrot, Fabienne, Mengozzi, Manuela, Ghezzi, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626850/
https://www.ncbi.nlm.nih.gov/pubmed/29033950
http://dx.doi.org/10.3389/fimmu.2017.01239

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