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Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study
Systemic sclerosis (SSc) is a rare multi-organ autoimmune disease characterized by progressive skin fibrosis. Inflammation, type 2 immunity, and fibrogenic processes are involved in disease development and may be affected by sphingolipids. However, details about early-stage pathophysiological mechan...
Autores principales: | Schmidt, Katrin G., Herrero San Juan, Martina, Trautmann, Sandra, Berninger, Lucija, Schwiebs, Anja, Ottenlinger, Florian M., Thomas, Dominique, Zaucke, Frank, Pfeilschifter, Josef M., Radeke, Heinfried H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626866/ https://www.ncbi.nlm.nih.gov/pubmed/29033951 http://dx.doi.org/10.3389/fimmu.2017.01242 |
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