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Time-Resolved Transposon Insertion Sequencing Reveals Genome-Wide Fitness Dynamics during Infection

Transposon insertion sequencing (TIS) is a powerful high-throughput genetic technique that is transforming functional genomics in prokaryotes, because it enables genome-wide mapping of the determinants of fitness. However, current approaches for analyzing TIS data assume that selective pressures are...

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Detalles Bibliográficos
Autores principales:	Yang, Guanhua, Billings, Gabriel, Hubbard, Troy P., Park, Joseph S., Yin Leung, Ka, Liu, Qin, Davis, Brigid M., Zhang, Yuanxing, Wang, Qiyao, Waldor, Matthew K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626973/ https://www.ncbi.nlm.nih.gov/pubmed/28974620 http://dx.doi.org/10.1128/mBio.01581-17

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