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The Infectious Basis of ACPA-Positive Rheumatoid Arthritis

Rheumatoid arthritis (RA) is associated with HLA-DRB1 shared epitope (HLA-DRB1SE) and anti-citrullinated protein autoantibodies (ACPAs). ACPAs precedes the onset of clinical and subclinical RA. There are strong data for three infectious agents as autoimmunity triggers in RA, namely Porphyromonas gin...

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Detalles Bibliográficos
Autores principales: Sakkas, Lazaros I., Daoussis, Dimitrios, Liossis, Stamatis-Nick, Bogdanos, Dimitrios P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627006/
https://www.ncbi.nlm.nih.gov/pubmed/29033912
http://dx.doi.org/10.3389/fmicb.2017.01853