Pathogenic CD8(+) T Cells Cause Increased Levels of VEGF-A in Experimental Malaria-Associated Acute Respiratory Distress Syndrome, but Therapeutic VEGFR Inhibition Is Not Effective

Malaria is a severe disease and kills over 400,000 people each year. Malarial complications are the main cause of death and include cerebral malaria and malaria-associated acute respiratory distress syndrome (MA-ARDS). Despite antimalarial treatment, lethality rates of MA-ARDS are still between 20 a...

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Detalles Bibliográficos
Autores principales: Pham, Thao-Thy, Verheijen, Melissa, Vandermosten, Leen, Deroost, Katrien, Knoops, Sofie, Van den Eynde, Kathleen, Boon, Louis, Janse, Chris J., Opdenakker, Ghislain, Van den Steen, Philippe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627041/
https://www.ncbi.nlm.nih.gov/pubmed/29034214
http://dx.doi.org/10.3389/fcimb.2017.00416

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