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A VLP-based vaccine provides complete protection against Nipah virus challenge following multiple-dose or single-dose vaccination schedules in a hamster model

Nipah virus is a highly lethal zoonotic paramyxovirus that was first recognized in Malaysia during an outbreak in 1998. During this outbreak, Nipah virus infection caused a severe febrile neurological disease in humans who worked in close contact with infected pigs. The case fatality rate in humans...

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Detalles Bibliográficos
Autores principales: Walpita, Pramila, Cong, Yu, Jahrling, Peter B., Rojas, Oscar, Postnikova, Elena, Yu, Shuiqing, Johns, Lisa, Holbrook, Michael. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627259/
https://www.ncbi.nlm.nih.gov/pubmed/29263876
http://dx.doi.org/10.1038/s41541-017-0023-7