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A VLP-based vaccine provides complete protection against Nipah virus challenge following multiple-dose or single-dose vaccination schedules in a hamster model
Nipah virus is a highly lethal zoonotic paramyxovirus that was first recognized in Malaysia during an outbreak in 1998. During this outbreak, Nipah virus infection caused a severe febrile neurological disease in humans who worked in close contact with infected pigs. The case fatality rate in humans...
Autores principales: | Walpita, Pramila, Cong, Yu, Jahrling, Peter B., Rojas, Oscar, Postnikova, Elena, Yu, Shuiqing, Johns, Lisa, Holbrook, Michael. R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627259/ https://www.ncbi.nlm.nih.gov/pubmed/29263876 http://dx.doi.org/10.1038/s41541-017-0023-7 |
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