Protein nanovaccine confers robust immunity against Toxoplasma

We designed and produced a self-assembling protein nanoparticle. This self-assembling protein nanoparticle contains five CD8(+) HLA-A03-11 supertypes-restricted epitopes from antigens expressed during Toxoplasma gondii’s lifecycle, the universal CD4(+) T cell epitope PADRE, and flagellin as a scaffo...

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Detalles Bibliográficos
Autores principales: El Bissati, Kamal, Zhou, Ying, Paulillo, Sara Maria, Raman, Senthil Kumar, Karch, Christopher P., Roberts, Craig W., Lanar, David E., Reed, Steve, Fox, Chris, Carter, Darrick, Alexander, Jeff, Sette, Alessandro, Sidney, John, Lorenzi, Hernan, Begeman, Ian J., Burkhard, Peter, McLeod, Rima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627305/
https://www.ncbi.nlm.nih.gov/pubmed/29263879
http://dx.doi.org/10.1038/s41541-017-0024-6

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