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Real-Time Imaging of a Single Gene Reveals Transcription-Initiated Local Confinement
Genome dynamics are intimately linked to the regulation of gene expression, the most fundamental mechanism in biology, yet we still do not know whether the very process of transcription drives spatial organization at specific gene loci. Here, we have optimized the ANCHOR/ParB DNA-labeling system for...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627313/ https://www.ncbi.nlm.nih.gov/pubmed/28978433 http://dx.doi.org/10.1016/j.bpj.2017.08.014 |