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Mesenchymal stromal cell therapy reduces lung inflammation and vascular remodeling and improves hemodynamics in experimental pulmonary arterial hypertension

BACKGROUND: Experimental research has reported beneficial effects of mesenchymal stromal cell (MSC) therapy in pulmonary arterial hypertension (PAH). However, these studies either were based on prophylactic protocols or assessed basic remodeling features without evaluating possible mechanisms. We an...

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Detalles Bibliográficos
Autores principales: de Mendonça, Lucas, Felix, Nathane S., Blanco, Natália G., Da Silva, Jaqueline S., Ferreira, Tatiana P., Abreu, Soraia C., Cruz, Fernanda F., Rocha, Nazareth, Silva, Patrícia M., Martins, Vanessa, Capelozzi, Vera L., Zapata-Sudo, Gizele, Rocco, Patricia R. M., Silva, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627397/
https://www.ncbi.nlm.nih.gov/pubmed/28974252
http://dx.doi.org/10.1186/s13287-017-0669-0