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Mesenchymal stromal cell therapy reduces lung inflammation and vascular remodeling and improves hemodynamics in experimental pulmonary arterial hypertension
BACKGROUND: Experimental research has reported beneficial effects of mesenchymal stromal cell (MSC) therapy in pulmonary arterial hypertension (PAH). However, these studies either were based on prophylactic protocols or assessed basic remodeling features without evaluating possible mechanisms. We an...
Autores principales: | de Mendonça, Lucas, Felix, Nathane S., Blanco, Natália G., Da Silva, Jaqueline S., Ferreira, Tatiana P., Abreu, Soraia C., Cruz, Fernanda F., Rocha, Nazareth, Silva, Patrícia M., Martins, Vanessa, Capelozzi, Vera L., Zapata-Sudo, Gizele, Rocco, Patricia R. M., Silva, Pedro L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627397/ https://www.ncbi.nlm.nih.gov/pubmed/28974252 http://dx.doi.org/10.1186/s13287-017-0669-0 |
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