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Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report

BACKGROUND: The Bacillus Calmette–Guérin vaccine, which is used for the prevention of tuberculosis, is considered protective against the severe forms of childhood tuberculosis. However, some serious adverse reactions including osteitis of the long bones can occur. CASE PRESENTATION: We report a case...

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Autores principales: Kheir, Abdelmoneim E. M., Ibrahim, Salah A., Abdelsatir, Azza, Bahar, Mustafa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627407/
https://www.ncbi.nlm.nih.gov/pubmed/28974253
http://dx.doi.org/10.1186/s13256-017-1446-5
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author Kheir, Abdelmoneim E. M.
Ibrahim, Salah A.
Abdelsatir, Azza
Bahar, Mustafa E.
author_facet Kheir, Abdelmoneim E. M.
Ibrahim, Salah A.
Abdelsatir, Azza
Bahar, Mustafa E.
author_sort Kheir, Abdelmoneim E. M.
collection PubMed
description BACKGROUND: The Bacillus Calmette–Guérin vaccine, which is used for the prevention of tuberculosis, is considered protective against the severe forms of childhood tuberculosis. However, some serious adverse reactions including osteitis of the long bones can occur. CASE PRESENTATION: We report a case of an 18-month-old Sudanese girl who presented at the age of 3 months with swelling of her left forearm following Bacillus Calmette–Guérin vaccination administered at birth. Radiological and histological investigations confirmed tuberculous osteitis of the distal radius. She responded very well to antituberculous treatment with complete healing at follow-up visits. To the best of our knowledge this is the first case report of osteitis of the radius following Bacillus Calmette–Guérin vaccination described from Sudan. CONCLUSIONS: Bacillus Calmette–Guérin osteitis, although rare, should be considered a possible complication of the Bacillus Calmette–Guérin vaccination, and early diagnosis and treatment are essential.
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spelling pubmed-56274072017-10-12 Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report Kheir, Abdelmoneim E. M. Ibrahim, Salah A. Abdelsatir, Azza Bahar, Mustafa E. J Med Case Rep Case Report BACKGROUND: The Bacillus Calmette–Guérin vaccine, which is used for the prevention of tuberculosis, is considered protective against the severe forms of childhood tuberculosis. However, some serious adverse reactions including osteitis of the long bones can occur. CASE PRESENTATION: We report a case of an 18-month-old Sudanese girl who presented at the age of 3 months with swelling of her left forearm following Bacillus Calmette–Guérin vaccination administered at birth. Radiological and histological investigations confirmed tuberculous osteitis of the distal radius. She responded very well to antituberculous treatment with complete healing at follow-up visits. To the best of our knowledge this is the first case report of osteitis of the radius following Bacillus Calmette–Guérin vaccination described from Sudan. CONCLUSIONS: Bacillus Calmette–Guérin osteitis, although rare, should be considered a possible complication of the Bacillus Calmette–Guérin vaccination, and early diagnosis and treatment are essential. BioMed Central 2017-10-04 /pmc/articles/PMC5627407/ /pubmed/28974253 http://dx.doi.org/10.1186/s13256-017-1446-5 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Kheir, Abdelmoneim E. M.
Ibrahim, Salah A.
Abdelsatir, Azza
Bahar, Mustafa E.
Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report
title Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report
title_full Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report
title_fullStr Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report
title_full_unstemmed Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report
title_short Osteitis of the radius following Bacillus Calmette–Guérin vaccination at birth: a case report
title_sort osteitis of the radius following bacillus calmette–guérin vaccination at birth: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627407/
https://www.ncbi.nlm.nih.gov/pubmed/28974253
http://dx.doi.org/10.1186/s13256-017-1446-5
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