The stem cell factor SALL4 is an essential transcriptional regulator in mixed lineage leukemia-rearranged leukemogenesis

BACKGROUND: The stem cell factor spalt-like transcription factor 4 (SALL4) plays important roles in normal hematopoiesis and also in leukemogenesis. We previously reported that SALL4 exerts its effect by recruiting important epigenetic factors such as DNA methyltransferases DNMT1 and lysine-specific...

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Detalles Bibliográficos
Autores principales: Yang, Lina, Liu, Li, Gao, Hong, Pinnamaneni, Jaya Pratap, Sanagasetti, Deepthi, Singh, Vivek P., Wang, Kai, Mathison, Megumi, Zhang, Qianzi, Chen, Fengju, Mo, Qianxing, Rosengart, Todd, Yang, Jianchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627455/
https://www.ncbi.nlm.nih.gov/pubmed/28974232
http://dx.doi.org/10.1186/s13045-017-0531-y

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