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Evaluation of a C57BL/6J x 129S1/SvImJ Hybrid Nestin-Thymidine Kinase Transgenic Mouse Model for Studying the Functional Significance of Exercise-Induced Adult Hippocampal Neurogenesis
New neurons are continuously generated in the adult hippocampus but their function remains a mystery. The nestin thymidine kinase (nestin-TK) transgenic method has been used for selective and conditional reduction of neurogenesis for the purpose of testing the functional significance of new neurons...
Autores principales: | Hamilton, G.F., Majdak, P., Miller, D.S., Bucko, P.J., Merritt, J.R., Krebs, C.P., Rhodes, J.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627510/ https://www.ncbi.nlm.nih.gov/pubmed/28989863 http://dx.doi.org/10.3233/BPL-150011 |
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