Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies

Deficiency of interleukin (IL)-36 receptor antagonist (DITRA) syndrome is a rare autosomal recessive disease caused by mutations in IL36RN. IL-36R is a cell surface receptor and a member of the IL1R family that is involved in inflammatory responses triggered in skin and other epithelial tissues. Acc...

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Detalles Bibliográficos
Autores principales: Ganesan, Rajkumar, Raymond, Ernest L., Mennerich, Detlev, Woska, Joseph R., Caviness, Gary, Grimaldi, Christine, Ahlberg, Jennifer, Perez, Rocio, Roberts, Simon, Yang, Danlin, Jerath, Kavita, Truncali, Kristopher, Frego, Lee, Sepulveda, Eliud, Gupta, Priyanka, Brown, Su-Ellen, Howell, Michael D., Canada, Keith A., Kroe-Barrett, Rachel, Fine, Jay S., Singh, Sanjaya, Mbow, M. Lamine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627585/
https://www.ncbi.nlm.nih.gov/pubmed/28726542
http://dx.doi.org/10.1080/19420862.2017.1353853

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