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Characterization of highly concentrated antibody solution - A toolbox for the description of protein long-term solution stability
High protein titers are gaining importance in biopharmaceutical industry. A major challenge in the development of highly concentrated mAb solutions is their long-term stability and often incalculable viscosity. The complexity of the molecule itself, as well as the various molecular interactions, mak...
Autores principales: | Schermeyer, Marie-Therese, Wöll, Anna K., Kokke, Bas, Eppink, Michel, Hubbuch, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627599/ https://www.ncbi.nlm.nih.gov/pubmed/28617076 http://dx.doi.org/10.1080/19420862.2017.1338222 |
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