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Characterization of highly concentrated antibody solution - A toolbox for the description of protein long-term solution stability

High protein titers are gaining importance in biopharmaceutical industry. A major challenge in the development of highly concentrated mAb solutions is their long-term stability and often incalculable viscosity. The complexity of the molecule itself, as well as the various molecular interactions, mak...

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Detalles Bibliográficos
Autores principales: Schermeyer, Marie-Therese, Wöll, Anna K., Kokke, Bas, Eppink, Michel, Hubbuch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627599/
https://www.ncbi.nlm.nih.gov/pubmed/28617076
http://dx.doi.org/10.1080/19420862.2017.1338222

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