Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease

Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression o...

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Detalles Bibliográficos
Autores principales: Gao, Shen, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2017
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627698/
https://www.ncbi.nlm.nih.gov/pubmed/29063061
http://dx.doi.org/10.1016/j.cdtm.2017.02.008
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author Gao, Shen
Liu, Jing
author_facet Gao, Shen
Liu, Jing
author_sort Gao, Shen
collection PubMed
description Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies.
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spelling pubmed-56276982017-10-23 Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease Gao, Shen Liu, Jing Chronic Dis Transl Med Perspective Atherosclerosis is a chronic, progressive disease which eventually leads to coronary heart disease (CHD), ischemic stroke and other atherosclerotic cardiovascular disease (ASCVD). Numerous studies have demonstrated an atherogenic role of oxidized low-density lipoprotein (ox-LDL) in the progression of ASCVD. This article briefly reviews the atherogenic mechanism of ox-LDL, the methods of measuring ox-LDL in the circulation, effect of medical therapy and life-style modification on ox-LDL level, and the association between circulating ox-LDL and atherosclerosis, including clinical ASCVD events and subclinical atherosclerosis, in observational studies. KeAi Publishing 2017-05-25 /pmc/articles/PMC5627698/ /pubmed/29063061 http://dx.doi.org/10.1016/j.cdtm.2017.02.008 Text en © 2017 Chinese Medical Association. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Perspective
Gao, Shen
Liu, Jing
Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_full Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_fullStr Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_full_unstemmed Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_short Association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
title_sort association between circulating oxidized low-density lipoprotein and atherosclerotic cardiovascular disease
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627698/
https://www.ncbi.nlm.nih.gov/pubmed/29063061
http://dx.doi.org/10.1016/j.cdtm.2017.02.008
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