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Tumor-targeted costimulation by using bi-specific aptamers
Aptamers are chemically synthesized oligonucleotides that can be easily engineered for cancer immunotherapy use. So far, most of the therapeutic aptamers described are antagonistic and block the function of a receptor or its soluble ligand. Recently, aptamers have been modified to act as agonists by...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627702/ https://www.ncbi.nlm.nih.gov/pubmed/28989946 http://dx.doi.org/10.14800/ccm.1333 |