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Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation

As the number of patients waiting to receive transplants increases, there is a need to explore all possible donation opportunities. In this case report, we describe the transplantation of a liver from a donor who died after ethylene glycol poisoning into a woman with alcoholic liver disease with cir...

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Autores principales: Burman, Alisha, Watson, Christopher J. E., Kosmoliaptsis, Vasilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627743/
https://www.ncbi.nlm.nih.gov/pubmed/29026875
http://dx.doi.org/10.1097/TXD.0000000000000729
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author Burman, Alisha
Watson, Christopher J. E.
Kosmoliaptsis, Vasilis
author_facet Burman, Alisha
Watson, Christopher J. E.
Kosmoliaptsis, Vasilis
author_sort Burman, Alisha
collection PubMed
description As the number of patients waiting to receive transplants increases, there is a need to explore all possible donation opportunities. In this case report, we describe the transplantation of a liver from a donor who died after ethylene glycol poisoning into a woman with alcoholic liver disease with cirrhosis and associated ascites. Donor management, including ethanol, fomepizol and haemodialysis, hastened clearance of ethylene glycol from the circulation, and after liver transplantation, the recipient exhibited no adverse effects suggestive of ethylene glycol toxicity, although recipient hepatic artery dissection and thrombosis necessitated retransplantation. Our experience suggests that donor death due to ethylene glycol intoxication should not contraindicate liver transplantation, particularly after appropriate donor management.
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spelling pubmed-56277432017-10-12 Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation Burman, Alisha Watson, Christopher J. E. Kosmoliaptsis, Vasilis Transplant Direct Liver Transplantation As the number of patients waiting to receive transplants increases, there is a need to explore all possible donation opportunities. In this case report, we describe the transplantation of a liver from a donor who died after ethylene glycol poisoning into a woman with alcoholic liver disease with cirrhosis and associated ascites. Donor management, including ethanol, fomepizol and haemodialysis, hastened clearance of ethylene glycol from the circulation, and after liver transplantation, the recipient exhibited no adverse effects suggestive of ethylene glycol toxicity, although recipient hepatic artery dissection and thrombosis necessitated retransplantation. Our experience suggests that donor death due to ethylene glycol intoxication should not contraindicate liver transplantation, particularly after appropriate donor management. Lippincott Williams & Wilkins 2017-09-08 /pmc/articles/PMC5627743/ /pubmed/29026875 http://dx.doi.org/10.1097/TXD.0000000000000729 Text en Copyright © 2017 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Liver Transplantation
Burman, Alisha
Watson, Christopher J. E.
Kosmoliaptsis, Vasilis
Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation
title Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation
title_full Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation
title_fullStr Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation
title_full_unstemmed Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation
title_short Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation
title_sort ethylene glycol poisoning should not contraindicate liver donation
topic Liver Transplantation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627743/
https://www.ncbi.nlm.nih.gov/pubmed/29026875
http://dx.doi.org/10.1097/TXD.0000000000000729
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