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Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation
As the number of patients waiting to receive transplants increases, there is a need to explore all possible donation opportunities. In this case report, we describe the transplantation of a liver from a donor who died after ethylene glycol poisoning into a woman with alcoholic liver disease with cir...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627743/ https://www.ncbi.nlm.nih.gov/pubmed/29026875 http://dx.doi.org/10.1097/TXD.0000000000000729 |
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author | Burman, Alisha Watson, Christopher J. E. Kosmoliaptsis, Vasilis |
author_facet | Burman, Alisha Watson, Christopher J. E. Kosmoliaptsis, Vasilis |
author_sort | Burman, Alisha |
collection | PubMed |
description | As the number of patients waiting to receive transplants increases, there is a need to explore all possible donation opportunities. In this case report, we describe the transplantation of a liver from a donor who died after ethylene glycol poisoning into a woman with alcoholic liver disease with cirrhosis and associated ascites. Donor management, including ethanol, fomepizol and haemodialysis, hastened clearance of ethylene glycol from the circulation, and after liver transplantation, the recipient exhibited no adverse effects suggestive of ethylene glycol toxicity, although recipient hepatic artery dissection and thrombosis necessitated retransplantation. Our experience suggests that donor death due to ethylene glycol intoxication should not contraindicate liver transplantation, particularly after appropriate donor management. |
format | Online Article Text |
id | pubmed-5627743 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-56277432017-10-12 Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation Burman, Alisha Watson, Christopher J. E. Kosmoliaptsis, Vasilis Transplant Direct Liver Transplantation As the number of patients waiting to receive transplants increases, there is a need to explore all possible donation opportunities. In this case report, we describe the transplantation of a liver from a donor who died after ethylene glycol poisoning into a woman with alcoholic liver disease with cirrhosis and associated ascites. Donor management, including ethanol, fomepizol and haemodialysis, hastened clearance of ethylene glycol from the circulation, and after liver transplantation, the recipient exhibited no adverse effects suggestive of ethylene glycol toxicity, although recipient hepatic artery dissection and thrombosis necessitated retransplantation. Our experience suggests that donor death due to ethylene glycol intoxication should not contraindicate liver transplantation, particularly after appropriate donor management. Lippincott Williams & Wilkins 2017-09-08 /pmc/articles/PMC5627743/ /pubmed/29026875 http://dx.doi.org/10.1097/TXD.0000000000000729 Text en Copyright © 2017 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Liver Transplantation Burman, Alisha Watson, Christopher J. E. Kosmoliaptsis, Vasilis Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation |
title | Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation |
title_full | Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation |
title_fullStr | Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation |
title_full_unstemmed | Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation |
title_short | Ethylene Glycol Poisoning Should Not Contraindicate Liver Donation |
title_sort | ethylene glycol poisoning should not contraindicate liver donation |
topic | Liver Transplantation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5627743/ https://www.ncbi.nlm.nih.gov/pubmed/29026875 http://dx.doi.org/10.1097/TXD.0000000000000729 |
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